Donor oocytes can be applied when it is impossible to retrieve a patient’s own oocytes or they cannot be used for various reasons. For example, in case of absence of ovaries or deterioration of their function, in case of absence of ovarian response to stimulation of ovulation or repeated unsuccessful IVF attempts, while obtaining low-quality embryos. In addition, donor oocytes can be used to achieve a pregnancy in women to whom, for various reasons, stimulation of the ovaries is contraindicative, as well as women with genetic diseases, to avoid their transfer to the offspring. Preimplantation genetic diagnosis (PGD) allows you to check embryos prior to their transfer, and if the results of PGD are not satisfactory, it is recommended to use donor egg cells.
Fertility naturally decreases with age. Until now, there are no methods for ovarian reserve supplementing. Effectiveness of infertility treatment in women over 35 years old significantly reduces, and the risk of chromosomal abnormalities increases, for instance, the risk of having children with Down syndrome increases several times.
The use of oocytes retrieved from young healthy female donors considerably increases the effectiveness of treatment. Thanks to the good quality of their oocytes, the chances of having a healthy baby increase dramatically.
Our donors undergo a comprehensive examination. Specialists of the Clinic carefully examine every donor (in accordance with the Order of the Ministry of Health of Ukraine No. 787 dated 09.09.2013), define their general state of health (donors have tests for hepatitis B and C, syphilis, HIV infection, sexually transmitted infections, etc.), conduct research of endocrine profile and also determine the donor’s karyotype. All oocyte donors must meet obligatory requirements: be in good physical and mental health, aged 35, have a healthy child of their own.
According to the legislation of Ukraine, the donor signs a relinquishment of parental rights to children born with the appliance of her biomaterial.
For some cases, it is optimal to use vitrified (cryopreserved) donor oocytes. If oocytes of the selected donor are available in the Clinic’s cryobank, patients can use them in the IVF protocol. Advantages of this option: lower cost, it is convenient to coordinate the transfer dates, no synchronization of the donor’s and recipient’s cycles is required. However, there are disadvantages. In other variants of protocol, patients have all oocytes obtained from the donor (usually about 10), it means that there are high chances for them to have several viable embryos of high quality. In a protocol with vitrified oocytes, patients receive only 5 vitrified donor’s cells. This reduces the number of embryos produced.
It should be mentioned that vitrification does not affect the quality of eggs and embryos.