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Time Lapse Embryo Selection

The method of in vitro fertilization is primarily aimed at creating a viable embryo and its further successful implantation. A very important stage of IVF is selection of the best embryos from all the obtained ones for their transfer to the uterine cavity.

After fertilization, embryos undergo a stage of cultivation, i.e. they grow and develop. In the process of cultivation, they are in a special incubator, in conditions as close to natural as possible. To assess how embryos develop and choose the best of them, the embryologist periodically extracts them from the incubator and inspects them with an inverted microscope, assessing the quality and pace of embryo development. However, even when embryos are briefly removed for inspection (less than a minute), the temperature and pH of the culture medium in which embryos are placed change, at each examination embryos are exposed to light — all these factors can adversely affect their development, since embryos are very sensitive to changes of conditions of the external environment.

In order to exclude external effect on embryos and avoid negative consequences, the Clinic introduced an advanced technology of continuous embryo observation – the Time Lapse Embryo Selection method. It makes it possible to inspect and evaluate the quality and pace of embryo development without opening an incubator.

For shooting low-intensity LED green light is used which 90% reduces the light load on the embryo compared to a standard examination under an ordinary microscope.

The maximum detailed video chronicle of early development of each embryo allows the embryologist to choose embryos with the best morphological parameters. In addition, an important indicator in assessing the quality and potential for implantation is the kinetics of development — the time in which the embryo passes from one stage of development to the next one.